Pharmacophore-based discovery of ligands for drug transporters
نویسندگان
چکیده
منابع مشابه
Amino Acid Transporters in Drug Discovery
Administered drugs interact with membrane transporters of epithelia, Blood Brain Barrier and other districts influencing their delivery and efficacy. Drugs can also be used as inhibitors of transporters involved in human pathology. Drug-transporter interactions are responsible of off-target effects contributing to toxicity. High Throughput Screening technologies increased the potential applicat...
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ژورنال
عنوان ژورنال: Advanced Drug Delivery Reviews
سال: 2006
ISSN: 0169-409X
DOI: 10.1016/j.addr.2006.09.006